Wittig Reaction of 1,3-Benzodithiol-2-ylidenetriphenylphosphorane with Carbon Disulfide

The Wittig Reaction

The Wittig Reaction

This so-called Wittig reaction has a number of advantages over other olefination methods; in particular, it occurs with total positional selectivity (that is, an alkene always directly replaces a carbonyl group). By comparison, a number of other carbonyl olefination reactions often occur with double-bond rearrangement. In addition, the factors that influence Eand Z-stereoselectivity are well un...

Mechanism of the Phospha-Wittig–Horner Reaction**

General. All reactions were performed under argon using Schlenk techniques. Diethyl ether and THF were freshly distilled from sodium/benzophenone prior to use. 1 H, 13 C and 31 P spectra were recorded on a 400 MHz and 300 MHz spectrometers. Chemical shifts (ppm) were reported and referenced to the internal signal of residual protic solvent. High resolution mass spectral analyses (HRMS) were per...

Using the Wittig reaction to produce alkenylcarbaboranes.

This communication reports the first use of the Wittig reaction to produce alkenylcarbaboranes.

Carbon disulfide.

The September 1998 issue of EHP contained two articles about the neurotoxicity of carbon disulfide. The "NIEHS News" article (1) reported on a collaborative study that involved scientists from the NIEHS (Nashville, TN). In this study, the neurotoxicity of carbon disulfide was detailed from the earliest molecular alterations to neurobehavioral findings to electrophysiologic and morphologic chang...